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Each subject recieved 0.2 mmol/kg of Gd(DTPA) 2 (Magnevist®, Bayer Healthcare) contrast agent, followed by a saline flush. Immediately after contrast administration , each subject walked for 10 minutes to promote diffusion of the contrast into synovial fluid and cartilage. Comparison of delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) using Inversion Recovery and Fast T1 Mapping Sequences T. C. Mamisch1, M. Dudda2, T. Hughes3, D. Burstein4, and Y-J. Kim 5 1Orthopaedic Surgery, University of Bern, Bern, Switzerland, 2Orthopaedic Surgery, Children's Hospital-Boston, Boston, MA, United States, 3Siemens Medical System, Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) was first described in 1996 as a nondestructive technique for quantitative measurements of glycosaminoglycan (GAG) concentration in articular cartilage samples [].Its translation to clinical platforms as a means of interrogating the molecular aspects of cartilage was demonstrated in 1997 with illustrative examples of apparent … 2014-11-01 2016-09-29 Assessment of degenerative changes of the cartilage is important in knee cartilage repair surgery. Magnetic Resonance Imaging (MRI) T2 mapping and delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC… software (Siemens).

Siemens er verdens største batterileverandør og vores energilagringssystemer bygger på anerkendte teknologier, der sikrer effektiv lagring og anvendelse af vedvarende energi til den lavest mulige pris. Vi leverer energilagringsløsninger til store såvel som til mindre anlæg. Thirty-five hips in 35 patients presenting with varying radiographic evidence of arthritis in the hip were imaged using a 3D isotropic fast T1 mapping dGEMRIC sequence (TR 15 msec, TE 3.27 msec, flip angles of 4.1 and 23.5 deg., Matrix size 192/192, 16 cm FoV, voxel size 0.8 x 0.8 x 0.8 mm) and a previously validated fast T1 mapping dGEMRIC sequence (voxel size 0.6 x 0.6 x 4 mm) for comparison. Jul 19, 2020 cartilage (dGEMRIC) index over 2 years as a measure of cartilage Siemens Magnetom Trio 3.0 Tesla (T) magnets (Siemens AG,. Erlangen Oct 22, 2013 Knee cartilage assessment with MRI (dGEMRIC) and subjective knee with a dedicated knee coil (Magnetom Vision; Siemens Medical.

| 2009-07-13 MAGNETOM Marketing Tool Kit Twenty six hips in 16 patients were scanned (14 left hips, 12 right hips).

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Images were analyzed by two independent raters for dGEMRIC indices, PsA MRI scores (PsAMRIS), and total cartilage thickness (TCT). dGEMRIC index was calculated by averaging the T1 val-ues in the corresponding 16 central slices (0.9 mm thick). Second, for each of the 4 central thick slices (4 mm thick-ness), the corresponding high resolution dGEMRIC index was calculated from the corresponding 4 thin slices (0.9 mm thickness) and compared. All image analyses were Then, sagittal dGEMRIC maps after equilibration in 1mM Gd-DTPA2-for 3 hours, were obtained in the same imaging plane and knee positions (Position A and B). In addition, sagittal T2, T2*, and dGEMRIC maps with the knee extended (flexion 0°) and the femoral shaft oriented 40° to B 0 (Position C) were obtained in two knees, to evaluate the isolated 2009-05-01 2021-01-20 2020-05-29 The MRI imaging was performed using a 1.5 T Siemens Avanto MRI machine (Siemens Healthcare GmbH, Erlangen, Germany).

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Results: Chondromalacia grade 2-3 had significantly higher CEST values (P = 0.001), lower dGEMRIC (T1-) values (P < 0.001) and higher T2 values (P < 0.001) when compared to the normal appearing cartilage. dGEMRIC and T2 mapping correlated moderately negative (Spearman coefficient r = -0.56, P = 0.0018) and T2 mapping and CEST moderately positive (r = 0.5, P = 0.007), while dGEMRIC and CEST did Elektrifiering, automation och digitalisering kräver innovativa lösningar: Upptäck Siemens som en stark partner, teknisk pionjär och ansvarig arbetsgivare. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) allows an objective, noninvasive, and longitudinal quantification of biochemical cartilage properties.

Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) is an imaging method for detecting early damage to cartilage. Furthermore, we defined dGEMRIC and T map- (Siemens Healthcare), which provides the protocols and inline cal- ping reference values for healthy and diseased cartilage of culation of parametric maps of T and T properties of the imaged 1 2 the wrist at 3T. tissue and automatically generates parametric color-coded maps. MR IMAGINGThe MR images were performed on a 1.5T magnet (Symphony; Siemens, Erlangen, Germany) using a quadrature knee coil (Siemens, Erlangen, Germany). Since we intended to perform the dGEMRIC analyses on the femoral and tibial articular cartilage from a single, 3 mm-thick slice through the median plane of the medial femoral condyle (Fig. 1 ROC-analysis demonstrated non-significant differences of T2 mapping vs CEST (P = 0.14), CEST vs dGEMRIC (P = 0.89), and T2 mapping vs dGEMRIC (P = 0.12). Conclusion: CEST is able to detect normal and damaged cartilage and is non-inferior in distinguishing both when compared to dGEMRIC and T2 mapping.
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The dGEMRIC Index of the medial diseased compartment correlated positively with both knee ﬂexor (r¼0.50, P¼0.001) and knee extensor Interestingly, when we compared results from our previously published article assessing the one year effect after intra-articular injection of autologous microfragmented adipose tissue, where out of 331 dGEMRIC measurements, 175 measurements (82.6%) were showing changes with a greater magnitude than 15%, while the remaining 37 dGEMRIC measurements (17.5%) were showing relevant decrease, it Methods: Twenty-seven participants (age = 28.8 ± 8.6 yrs; BMI = 24.2 ± 2.3 kg m −2; 44% females) diagnosed with FAI syndrome (cam-, pincer- or combined-type FAI morphology concurrent with symptoms) underwent hip MRI with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in one of two 3T scanners (Siemens Prisma, Siemens Skyra). The using 3D dGEMRIC at two different doses of the contrast agent Gd-DTPA2-. Methods: The right knee in 12 asymptomatic volunteers was examined using a 3D Look-Locker sequence on two occasions after an intravenous injection of a double or triple dose of Gd-DTPA2-(0.2 or 0.3 mmol/kg body weight).

Method: Sixty-nine subjects were prospectively included (median age, 42 years; male/female = 32/37) in three cohorts: 10 healthy volunteers, 40 patients with clinically suspected This definition approximates grade 2 knee OA based on the Kellgren and Lawrence scale 36 . MRISubjects were investigated with dGEMRIC 20.6 years (mean; range 18e23) after the injury, using a standard 1.5 T MRI system with a dedicated knee coil (Magnetom Vision; Siemens Medical Solutions, Erlangen, Germany). MRI with dGEMRIC was more sensitive than morphological MRI, and lower dGEMRIC values were found for clock positions with impingement as detected on 3D-CT. This could aid in patient-specific diagnosis of FAI, preoperative patient selection, and surgical decision making to identify patients with cartilage damage who are at risk for inferior outcomes after hip arthroscopy.
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Dept. of Orthopaedic Surgery, Children’s Hospital Boston, Harvard Medical School, Boston, USA Clinical Application of delayed Gadolinum Enhanded MRI of Cartilage (dGEMRIC) Marcel Dudda, M.D.; Young Jo Kim, M.D., Ph.D.

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Medical Radiation Physics, Malmö - Research Outputs - Lund

Images were analyzed by two independent raters for dGEMRIC indices, PsA MRI scores (PsAMRIS) and total Apr 17, 2019 the manual 3-D analysis of regional patterns of dGEMRIC index 3T scanner ( Trio; Siemens, Erlangen, Germany) [44] using a. 6-channel av C Siversson — BMI body mass index. dGEMRIC delayed gadolinium-enhanced MRI of cartilage All data were acquired on a 1.5 Tesla Siemens Sonata whole-body scanner USING AUTOMATIC EXPOSURE CONTROL IN CT – SIEMENS CARE DOSE disease in young adulthood: a 21-year follow-up study including dGEMRIC. Introduction: dGEMRIC (delayed Gadolinium Enhanced Magnetic (MR5) and Siemens Prisma 3 T (MR6), using a standard head receive coil.

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Activities not related to the present article: is a consultant for Bracco; institution has grants/grants pending from Siemens, Bayer, GE Healthcare, and Bracco. Other relationships: disclosed no relevant relationships. BACKGROUND: Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a validated technique for evaluating cartilage health in developmental dysplasia of the hip (DDH), which can be a helpful prognosticator for the response to surgical treatments.

dGEMRIC was performed on a 1.5T Siemens Symphony magnet . Each subject recieved 0.2 mmol/kg of Gd(DTPA) 2 (Magnevist®, Bayer Healthcare) contrast agent, followed by a saline flush. Immediately after contrast administration , each subject walked for 10 minutes to promote diffusion of the contrast into synovial fluid and cartilage.